{"id":7939,"date":"2019-01-28T14:07:28","date_gmt":"2019-01-28T21:07:28","guid":{"rendered":"https:\/\/crism.ca\/?page_id=7939"},"modified":"2026-09-30T12:57:47","modified_gmt":"2026-09-30T18:57:47","slug":"detoxification-and-withdrawal-management","status":"publish","type":"page","link":"https:\/\/crism.ca\/fr\/detoxification-and-withdrawal-management\/","title":{"rendered":"D\u00e9sintoxication et gestion du sevrage"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7939\" class=\"elementor elementor-7939\" wpc-filter-elementor-widget=\"1\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4b0a96b8 elementor-section-full_width elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no\" data-id=\"4b0a96b8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-115632d0\" data-id=\"115632d0\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3bf4db1d elementor-section-full_width elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no\" data-id=\"3bf4db1d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3d1ec170\" data-id=\"3d1ec170\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bcba97d elementor-widget-tablet__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"bcba97d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Implementation<br>Science Progam<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14a88b elementor-widget__width-initial elementor-widget-tablet__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"14a88b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Ontario Node<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-63f5635c\" data-id=\"63f5635c\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7e35451b elementor-widget-tablet__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"7e35451b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Detoxification and Withdrawal Management<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-48a0ea9c elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no\" data-id=\"48a0ea9c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-60fe4abf elementor-invisible\" data-id=\"60fe4abf\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-4f485b25 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no\" data-id=\"4f485b25\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d39fffc\" data-id=\"d39fffc\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-640b1011 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"640b1011\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5dbf35f5 elementor-widget elementor-widget-heading\" data-id=\"5dbf35f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Principal Investigators<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-438fa345 elementor-cta--skin-cover elementor-cta--valign-middle elementor-animated-content elementor-bg-transform elementor-bg-transform-zoom-in elementor-widget elementor-widget-call-to-action\" data-id=\"438fa345\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta\">\n\t\t\t\t\t<div class=\"elementor-cta__bg-wrapper\">\n\t\t\t\t<div class=\"elementor-cta__bg elementor-bg\" style=\"background-image: url(https:\/\/crism.ca\/wp-content\/uploads\/2026\/09\/Brian-Rush-900-x-750.jpg);\" role=\"img\" aria-label=\"Brian-Rush-900-x-750\"><\/div>\n\t\t\t\t<div class=\"elementor-cta__bg-overlay\"><\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item elementor-animated-item--grow\">\n\t\t\t\t\t\tBrian Rush\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-cta__button-wrapper elementor-cta__content-item elementor-content-item elementor-animated-item--grow\">\n\t\t\t\t\t<a class=\"elementor-cta__button elementor-button elementor-size-\" href=\"https:\/\/hriresearch.com\/about-us\/our-people\/scientists\/brian-rush\/\" target=\"_blank\">\n\t\t\t\t\t\tabout\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e248b86 elementor-cta--skin-cover elementor-cta--valign-middle elementor-animated-content elementor-bg-transform elementor-bg-transform-zoom-in elementor-widget elementor-widget-call-to-action\" data-id=\"5e248b86\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"call-to-action.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-cta\">\n\t\t\t\t\t<div class=\"elementor-cta__bg-wrapper\">\n\t\t\t\t<div class=\"elementor-cta__bg elementor-bg\" style=\"background-image: url(https:\/\/crism.ca\/wp-content\/uploads\/2025\/08\/Jurgen-Rehm-Optimized-jpg.webp);\" role=\"img\" aria-label=\"Jurgen-Rehm-Optimized-jpg\"><\/div>\n\t\t\t\t<div class=\"elementor-cta__bg-overlay\"><\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-cta__content\">\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<h2 class=\"elementor-cta__title elementor-cta__content-item elementor-content-item elementor-animated-item--grow\">\n\t\t\t\t\t\tJ\u00fcrgen Rehm\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-cta__button-wrapper elementor-cta__content-item elementor-content-item elementor-animated-item--grow\">\n\t\t\t\t\t<a class=\"elementor-cta__button elementor-button elementor-size-\" href=\"https:\/\/www.camh.ca\/500.html?aspxerrorpath=\/science-and-research\/science-and-research-staff-directory\/jurgenrehm\" target=\"_blank\">\n\t\t\t\t\t\tabout\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5aa4387d\" data-id=\"5aa4387d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6d979390 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"6d979390\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-38a46a1e elementor-widget elementor-widget-heading\" data-id=\"38a46a1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Leadership Group<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-17531a67 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"17531a67\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><strong>Nikki Bozinoff &amp; Tara Elton-Marshall<\/strong> (CAMH, ON);<\/li><li><strong>Keith Ahamad<\/strong> (BCCSU, BC);<\/li><li><strong>Annie Talbot<\/strong> (University of Montreal, QC);<\/li><li><strong>Samuel Hickcox<\/strong> (Nova Scotia Health Authority, NS);<\/li><li><strong>Helen Bouman<\/strong> (Albert Health Services, AB)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-747a4202 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no\" data-id=\"747a4202\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2c2705d0 elementor-invisible\" data-id=\"2c2705d0\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2b6ecf25 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"2b6ecf25\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5fef9a68 elementor-widget-tablet__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"5fef9a68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Context<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5dc34875 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"5dc34875\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Given the extensive population sizes with opioid use disorders and related harms forming a core part of the \u2018opioid crisis\u2019, the comprehensive and effective delivery of evidence-based treatment interventions constitutes a key element of the required interventions strategy. Treatment interventions for opioid use disorder consist mainly of long-term, e.g., opioid pharmacotherapy, treatment as a \u2018first-line response\u2019 option. There are, however, other therapeutic interventions which, for various reasons (e.g., limited OAT infrastructure, resources or expertise), are offered or practiced in Canada, including so-called \u2018detoxification\/withdrawal management\u2019 approaches. Some of these, as currently practiced, are based on a minimal evidence base. Still, also relatively diversified practices across Canada, and include considerable risk for harm (e.g., overdose due to lowered tolerance) to the patient, while for others (e.g., opioid tapering, naltrexone provision), evidence is only slowly emerging. Overall, minimal evidence-based guidance on these approaches currently prevails, which this project aims to address and improve.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-297c8059\" data-id=\"297c8059\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4b8bbc02 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"4b8bbc02\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;motion_fx_translateY_effect&quot;:&quot;yes&quot;,&quot;motion_fx_translateY_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1,&quot;sizes&quot;:[]},&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;motion_fx_translateY_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"5333\" height=\"7999\" src=\"https:\/\/crism.ca\/wp-content\/uploads\/2025\/08\/hands-holding-pills-gradient-background.jpg\" class=\"attachment-full size-full wp-image-14539\" alt=\"\" srcset=\"https:\/\/crism.ca\/wp-content\/uploads\/2025\/08\/hands-holding-pills-gradient-background.jpg 5333w, https:\/\/crism.ca\/wp-content\/uploads\/2025\/08\/hands-holding-pills-gradient-background-200x300.jpg 200w, https:\/\/crism.ca\/wp-content\/uploads\/2025\/08\/hands-holding-pills-gradient-background-768x1152.jpg 768w, https:\/\/crism.ca\/wp-content\/uploads\/2025\/08\/hands-holding-pills-gradient-background-1024x1536.jpg 1024w\" sizes=\"(max-width: 5333px) 100vw, 5333px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5bf4f80f elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no\" data-id=\"5bf4f80f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-263f60a3 elementor-invisible\" data-id=\"263f60a3\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6090c71a elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"6090c71a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e8db6fe elementor-widget-tablet__width-inherit elementor-widget elementor-widget-heading\" data-id=\"4e8db6fe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Project Components<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-615538ec elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"615538ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Environmental Scan of Detoxification\/Withdrawal Management Practice and Needs Across Canada<\/strong><\/p><p>Detoxification and\/or withdrawal management approaches to opioid use disorders are provided and practiced in a sizeable number of institutions or facilities across Canada; many of these practices occur based on non-existent and\/or questionable evidence-based and with considerable risk to acute harm (e.g., accidental overdose death) to patients. At the same time, there appears to be a need for evidence-based guidance or support for opioid detoxification\/withdrawal management approaches, as driven either by patient and or system\/infrastructure needs or demands (e.g., where patients prefer to be off opioids or environments where capacity or skills for OAT do not exist).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-df9592a elementor-align-left elementor-widget elementor-widget-button\" data-id=\"df9592a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/crism.ca\/wp-content\/uploads\/2021\/06\/WMSFINALReportJune2021.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Access the Environmental Scan<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0412f80 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"0412f80\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Development of Opioid Detoxification\/withdrawal Management review and \u2018Best Practice\u2019 Document<\/strong><\/p><p>Opioid-related detoxification and withdrawal management approaches have their place in the continuum or spectrum of therapeutic interventions. There are several different approaches to opioid-related detoxification\/withdrawal management. While these include or are supported by limited, mixed, or controversial evidence bases at best, actual delivery and practice often occurs in a non-evidence-based fashion (e.g., drug-free opioid detoxification). For other elements, e.g. opioid tapering and or naltrexone provision (e.g., as detoxification aftercare), the evidence base is limited but evolving, also since relevant therapeutic practices and\/or medications are relatively new. Objectives include:<\/p><ul><li>Conduct a scoping\/narrative review of the current evidence on opioid disorder-related detoxification and withdrawal management (including opioid tapering, naltrexone provisions) practices, safety issues, and outcomes, i.e. focusing on therapeutic approaches to opioid disorders that are not geared towards long-term opioid pharmacotherapy treatment.<\/li><li>Create an evidence-based best practice document on opioid disorder-related detoxification and withdrawal management.<\/li><li>Develop various knowledge translation tools and strategies to engage relevant providers and stakeholders.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ac985f5 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"ac985f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/crism.ca\/wp-content\/uploads\/2023\/01\/CRISM-Withdrawal-Management-Guidance-Final.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Access the Guidance Document<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>ImplementationScience Progam Ontario Node Detoxification and Withdrawal Management Principal Investigators Brian Rush about J\u00fcrgen Rehm about Leadership Group Nikki Bozinoff &amp; Tara Elton-Marshall (CAMH, ON); Keith Ahamad (BCCSU, BC); Annie Talbot (University of Montreal, QC); Samuel Hickcox (Nova Scotia Health Authority, NS); Helen Bouman (Albert Health Services, AB) Context Given the extensive population sizes with opioid use disorders and related harms forming a core part of the \u2018opioid crisis\u2019, the comprehensive and effective delivery of evidence-based treatment interventions constitutes a key element of the required interventions strategy. Treatment interventions for opioid use disorder consist mainly of long-term, e.g., opioid pharmacotherapy, treatment as a \u2018first-line response\u2019 option. There are, however, other therapeutic interventions which, for various reasons (e.g., limited OAT infrastructure, resources or expertise), are offered or practiced in Canada, including so-called \u2018detoxification\/withdrawal management\u2019 approaches. Some of these, as currently practiced, are based on a minimal evidence base. Still, also relatively diversified practices across Canada, and include considerable risk for harm (e.g., overdose due to lowered tolerance) to the patient, while for others (e.g., opioid tapering, naltrexone provision), evidence is only slowly emerging. Overall, minimal evidence-based guidance on these approaches currently prevails, which this project aims to address and improve. Project Components Environmental Scan of Detoxification\/Withdrawal Management Practice and Needs Across Canada Detoxification and\/or withdrawal management approaches to opioid use disorders are provided and practiced in a sizeable number of institutions or facilities across Canada; many of these practices occur based on non-existent and\/or questionable evidence-based and with considerable risk to acute harm (e.g., accidental overdose death) to patients. At the same time, there appears to be a need for evidence-based guidance or support for opioid detoxification\/withdrawal management approaches, as driven either by patient and or system\/infrastructure needs or demands (e.g., where patients prefer to be off opioids or environments where capacity or skills for OAT do not exist). Access the Environmental Scan Development of Opioid Detoxification\/withdrawal Management review and \u2018Best Practice\u2019 Document Opioid-related detoxification and withdrawal management approaches have their place in the continuum or spectrum of therapeutic interventions. There are several different approaches to opioid-related detoxification\/withdrawal management. While these include or are supported by limited, mixed, or controversial evidence bases at best, actual delivery and practice often occurs in a non-evidence-based fashion (e.g., drug-free opioid detoxification). For other elements, e.g. opioid tapering and or naltrexone provision (e.g., as detoxification aftercare), the evidence base is limited but evolving, also since relevant therapeutic practices and\/or medications are relatively new. Objectives include: Conduct a scoping\/narrative review of the current evidence on opioid disorder-related detoxification and withdrawal management (including opioid tapering, naltrexone provisions) practices, safety issues, and outcomes, i.e. focusing on therapeutic approaches to opioid disorders that are not geared towards long-term opioid pharmacotherapy treatment. Create an evidence-based best practice document on opioid disorder-related detoxification and withdrawal management. Develop various knowledge translation tools and strategies to engage relevant providers and stakeholders. Access the Guidance Document<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"folder":[],"wf_page_folders":[368],"class_list":["post-7939","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Detoxification and Withdrawal Management - CRISM<\/title>\n<meta name=\"description\" content=\"Explore CRISM guidance on opioid detoxification and withdrawal management, including evidence review, best practices, and clinical implementation tools.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/crism.ca\/fr\/detoxification-and-withdrawal-management\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Detoxification and Withdrawal Management - 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